Adjuntamos la nota y links de Jounal Watch, con los mejores artículos para Medicina Familiar y General en 2010.

Esperamos les sean de interés, y les deseamos un excelente 2011 a todos. ¡Felicidades!

General Medicine Most-Read Stories of 2010

Our readers choose their favorite stories from 2010.

Each year, the editors of Journal Watch General Medicine select and comment on the most important themes in clinical research; we’ll continue this tradition with our 2010 Year in Review. We’re also repeating a feature that we introduced in 2009 — highlighting the 10 stories that our online readers (both generalists and specialists) visited most often. No dominant theme or pattern emerged in the 2010 Most-Read list — this fact probably reflects the heterogeneity of the topics we cover, and the breadth of interests of our online readership — but we hope you’ll enjoy looking back at these stories and considering how they influenced your practice in 2010.

Best wishes for 2011.

Allan S. Brett, MD, Editor-in-Chief, Journal Watch General Medicine and the Journal Watch General Medicine Editors

General Medicine Top Stories of 2010: Most Read

SUMMARY AND COMMENT

Analgesia: Are Acetaminophen/NSAID Combinations More Effective Than One Drug Alone?

A systematic review indicates that combinations are more effective for relieving acute pain.

  • Reviewing:
  • Ong CK et al. Anesth Analg 2010 Apr; 110:1170.

SUMMARY AND COMMENT

Dopamine vs. Norepinephrine in Treatment of Shock

A large randomized trial shows no difference in death rates with the two agents overall but significantly higher mortality with dopamine among patients with cardiogenic shock.

  • Reviewing:
  • De Backer D et al. N Engl J Med 2010 Mar 4; 362:779.
    Levy JH. N Engl J Med 2010 Mar 4; 362:841.

SUMMARY AND COMMENT

Proton-Pump Inhibitor Dosing and Negative Consequences

Four studies about the effects of PPI therapy

  • Reviewing:
  • Wang C-H et al. Arch Intern Med 2010 May 10; 170:751.
    Gray SL et al. Arch Intern Med 2010 May 10; 170:765.
    Linsky A et al. Arch Intern Med 2010 May 10; 170:772.
    Howell MD et al. Arch Intern Med 2010 May 10; 170:784.
    Katz MH. Arch Intern Med 2010 May 10; 170:747.

SUMMARY AND COMMENT

The ACCORD Lipid Study: Fenofibrate Doesn’t Help

Although triglyceride levels improved markedly with fenofibrate, incidence of adverse cardiovascular events was not affected.

  • Reviewing:
  • The ACCORD Study Group. N Engl J Med 2010 Mar 14.

SUMMARY AND COMMENT

Aspirin for Primary Prevention in Patients with Diabetes

Recommendations from three professional organizations

  • Reviewing:
  • Pignone M et al. Circulation 2010 Jun 22; 121:2694.

SUMMARY AND COMMENT

Monoarticular Arthritis: Which Patients to Treat for Gout?

A new clinical score supports decision making.

  • Reviewing:
  • Janssens HJEM et al. Arch Intern Med 2010 Jul 12; 170:1120.

SUMMARY AND COMMENT

Self-Management for Hypertension

Two interventions helped patients reach blood pressure goals.

  • Reviewing:
  • Bosworth HB et al. Ann Intern Med 2009 Nov 17; 151:687.

SUMMARY AND COMMENT

The ACCORD Blood Pressure Study: What Target for High-Risk Diabetic Patients?

Achieving systolic blood pressure levels lower than 140 mm Hg does not prevent adverse cardiovascular events.

  • Reviewing:
  • The ACCORD Study Group. N Engl J Med 2010 Mar 14.

SUMMARY AND COMMENT

Lipids, Apolipoproteins, and Vascular Disease: What to Measure?

Either total and HDL cholesterol, or apolipoproteins, fasting or not, are equally accurate.

  • Reviewing:
  • Di Angelantonio E et al. for the Emerging Risk Factors Collaboration. JAMA 2009 Nov 11; 302:1993.

SUMMARY AND COMMENT

Tranexamic Acid Reduces Mortality After Major Trauma

This promising new therapy is inexpensive and easy to administer.

  • Reviewing:
  • CRASH-2 trial collaborators. Lancet 2010 Jun 15.
    Levy JH. Lancet 2010 Jun 15.

Published in Journal Watch General Medicine December 28, 2010